Overview of Nutritional Status and Symptoms of Diabetic Gastroparesis in Patients With Type 2 Diabetes Mellitus with Uncontrolled Blood Glucose Levels
Abstract
Gastroparesis is a complication experienced by 20% - 50% of chronic diabetes mellitus patients with poor glycemic control. Hyperglycemia will slow down gastric emptying thereby reducing oral intake and mismatch of nutrient absorption which causes impaired nutritional status. Objective: to determine the nutritional status and symptoms of diabetic gastroparesis in type 2 diabetes mellitus patients with uncontrolled blood glucose levels. Method: Quantitative descriptive study on type 2 DM patients at RSAU Dr. M. Salamun. The sampling technique uses consecutive sampling with a sample size of 82 subjects. Data were obtained through gastrointestinal symptom score (GSS) questionnaires, height and weight checks, and patient medical records. Furthermore, the data results will be processed using univariate analysis. The questionnaire is considered reliable with the results of the reliability test of the crombach alpha value >0.50. Result: 71.9% of respondents experienced symptoms of diabetic gastroparesis with normal nutritional status (37.1%) and obesity (37.1%). The majority were female, ≥60 years old, and 1-5 years of DM. Conclusion: Health education and intervention in modifying lifestyle better so that it can control blood glycemia and make a diet that is suitable for patients with gastroparesis so that it can minimise the symptoms of gastroparesis experienced.
References
Adam, B., Liebregts, T., Saadat-Gilani, K., Vinson, B., & Holtmann, G. (2005). Validation of the gastrointestinal symptom score for the assessment of symptoms in patients with functional dyspepsia. Alimentary Pharmacology and Therapeutics, 22(4), 357–363. https://doi.org/10.1111/j.1365-2036.2005.02572.x
Alanazi, B. D., Alhablani, M., Alanazi, A., Balawi, M. M. al, Alamrani, A. S., Albalawi, N. A., Rfadh, S. A., Alfuhaymani, A. M., & Hashem, F. A. al. (2022). Prevalence and Determinants of Gastroparesis Symptoms among T2DM Patients in Tabuk City. Journal of Pharmaceutical Research International, 47–56. https://doi.org/10.9734/jpri/2022/v34i42a36293
Aljaras, R. M., Abu-Farsakh, N. M., Beas, R. M., Montalvan-Sanchez, E. E. M., Haidar, M. M., Karkash, A. M., Ramirez-Rojas, M. M., & Calderon, G. M. (2022). Nutritional Aspects in Patients with Gastroparesis: Normal BMI Despite Abnormal Intake! The American Journal of Gastroenterology. https://doi.org/10.14309/01.ajg.0000858760.29251.49
Amjad, W., Doycheva, I., Kamal, F., Malik, A., Pandu, A., Shabbir, M. A., Mumtaz, M., Batool, A., & Ukleja, A. (2022). Clinical predictors of symptom improvement failure in gastroparesis. Annals of Gastroenterology, 35(2), 119–126. https://doi.org/10.20524/aog.2022.0696
Arania, R., Triwahyuni, T., Esfandiari, F., Rama Nugraha, F., Patologi, D., Rumah, A., Umum, S., & Moeloek, A. (2021). Hubungan Antara Usia, Jenis Kelamin, dan Tingkat Pendidikan Dengan Kejadian Diabetes Melitus di Klinik Mardi Waluyo Lampung Tengah. Jurnal Medika Malahayati (Vol. 5, Issue 3).
Asghar, S., Asghar, S., Shahid, S., Sajjad, H., Abdul Nasir, J., & Usman, M. (2023). Gastroparesis-Related Symptoms in Patients with Type 2 Diabetes Mellitus: Early Detection, Risk Factors, and Prevalence. Cureus. https://doi.org/10.7759/cureus.35787
Aswath, G. S., Foris, L. A., Ashwath, A. K., & Patel, K. (2023). Diabetic Gastroparesis. NCBI. https://www.ncbi.nlm.nih.gov/books/NBK430794/
Barrett, A. C., Johnson, K. P., Halabi, M. El, & Parkman, H. P. (2023). Meal-eating characteristics among patients with symptoms of gastroparesis: Relationships to delays in gastric emptying. Neurogastroenterology & Motility, 35(11). https://doi.org/https://doi.org/10.1111/nmo.14661
Bharucha, A. E., Kudva, Y. C., & Prichard, D. O. (2019). Diabetic Gastroparesis. In Endocrine Reviews (Vol. 40, Issue 5, pp. 1318–1352). Oxford University Press. https://doi.org/10.1210/er.2018-00161
Camilleri, M., & Sanders, K. M. (2022). Gastroparesis. Gastroenterology, 162(1), 68-87.e1. https://doi.org/10.1053/j.gastro.2021.10.028
Fandinata, S. S., & Ernawati, I. (2020). Management Terapi Pada Penyakit Degeneratif (1st ed.). Graniti. www.penerbitgraniti.com
Farmer, A. D., Bruckner-Holt, C. E., Schwartz, S., Sadler, E., & Kadirkamanthan, S. (2019). Diabetic Gastroparesis: Perspectives from a Patient and Health Care Providers. Journal of Patient-Centered Research and Reviews, 6(2), 148–157. https://doi.org/10.17294/2330-0698.1689
Hagopian, G. G., Johnson, K. P., Shahsavari, D., & Parkman, H. P. (2022). Meal Eating Characteristics of Patients with Gastroparesis. Digestive Diseases and Sciences, 67(8), 3872–3880. https://doi.org/10.1007/s10620-021-07190-0
Imansary, Y., Yunus, M., & Gayatri, R. W. (2021). The Correlation Between Physical Activity, Body Mass Index (BMI), and Abdominal Circumference with Type 2 Diabetes Mellitus (DM) Cases at Public. Atlantis Press International B.V, 36. https://doi.org/10.2991/ahsr.k.210707.021
Jalleh, R., Marathe, C. S., Rayner, C. K., Jones, K. L., & Horowitz, M. (2019). Diabetic Gastroparesis and Glycaemic Control. Current Diabetes Reports, 19(12). https://doi.org/10.1007/s11892-019-1281-8
Kim, B. J., & Kuo, B. (2019). Gastroparesis and functional dyspepsia: A blurring distinction of pathophysiology and treatment. Journal of Neurogastroenterology and Motility, 25(1), 27–35. https://doi.org/10.5056/jnm18162
Kostitska, I. O., Mankovsky, B. M., Urbanovych, A. M., Zhurakivska, O. Y., Tymoshchuk, O. v., & Basiuha, I. O. (2019). Risk factors and early detection of gastroparesis in patients with type 2 diabetes mellitus. Regulatory Mechanisms in Biosystems, 10(1), 56–62. https://doi.org/10.15421/021909
Kurniawan, A., & Hanjaya Suwandi, B. (2019). Diabetic Gastroenteropathy: A Complication of Diabetes Mellitus. Acta Medica Indonesiana, 51(3), 263–271. https://www.researchgate.net/publication/337150259
Lee, J., Park, H. L., Park, S. Y., Lim, C. H., Kim, M. H., Lee, J. M., Chang, S. A., & Oh, J. H. (2024). Gastroparesis might not be uncommon in patients with diabetes mellitus in a real-world clinical setting: a cohort study. BMC Gastroenterology, 24(1). https://doi.org/10.1186/s12876-023-03106-6
Mukhyarjon, M., Tresia Pardede, I., & Amelia Putri, W. (2021). Gambaran Status Gizi Pasien Diabetes Melitus Tipe 2 Berdasarkan Antropometri. Journal of Medical Science, 41–47.
Uppaluri, S., Jain, M. A., Ali, H., Shingala, J., Amin, D., Ajwani, T., Fatima, I., Patel, N., Kaka, N., Sethi, Y., & Kapoor, N. (2024). Pathogenesis and management of diabetic gastroparesis: An updated clinically oriented review. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 18(3), 102994. https://doi.org/10.1016/j.dsx.2024.102994
Pramesti, K. (2023). Pengaruh Hiperglikemia Terhadap Gastroparesis Diabetik Pada Pasien Diabetes Melitus di Klinik Rawat Jalan RSD Dr. Soebandi. Repository Universitas Jember.
Sullivan, A., Temperley, L., & Ruban, A. (2020). Pathophysiology, Aetiology and Treatment of Gastroparesis. In Digestive Diseases and Sciences (Vol. 65, Issue 6, pp. 1615–1631). Springer. https://doi.org/10.1007/s10620-020-06287-2
Syed, A. R., Wolfe, M. M., & Calles-Escandon, J. (2020). Epidemiology and Diagnosis of Gastroparesis in the United States: A Population-based Study. Journal of Clinical Gastroenterology, 54(1), 50–54. https://doi.org/10.1097/MCG.0000000000001231
Wulandari, S. D., & Adelina, R. (2020). Hubungan Status Antropometri Dengan kadar Glukosa Darah, Kadar HbA1c dan Pola Makan Pada Penderita Diabetes Melitus Tipe 2 di Puskesmas Tarik Kabupaten Sidoarjo. Media Gizi Pangan, 27.
Ye, Y., Yin, Y., Huh, S. Y., Almansa, C., Bennett, D., & Camilleri, M. (2022). Epidemiology, Etiology, and Treatment of Gastroparesis: Real-World Evidence from a Large US National Claims Database. Gastroenterology, 162(1), 109-121.e5. https://doi.org/10.1053/j.gastro.2021.09.064
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