Correlation of Hemoglobin A1C with Fasting Blood Plasma Glucose in Patients with Diabetes Mellitus and Its Implication as A Marker of Glucose Control

Putu Dyah Sartika Sari; I Nyoman Arsana; Ni Ketut Ayu Juliasih

doi:10.37287/ijghr.v6i5.3492

Putu Dyah Sartika Sari Faculty of Information Technology and Science, Universitas Hindu Indonesia
I Nyoman Arsana Faculty of Information Technology and Science, Universitas Hindu Indonesia
Ni Ketut Ayu Juliasih Faculty of Information Technology and Science, Universitas Hindu Indonesia

DOI: https://doi.org/10.37287/ijghr.v6i5.3492

Keywords: blood plasma glucose, degenerative disease, diabetes mellitus, glycemic control, HbA1c

Abstract

Diabetes mellitus (DM) is a chronic disease whose prevalence continues to increase globally. Objective: This study aimed to analyze the correlation between hemoglobin A1c (HbA1c) and fasting blood plasma glucose (GDP) in patients with diabetes mellitus and its implications as a marker of glucose control. Method: A cross-sectional study was conducted using the medical records of 299 patients with diabetes mellitus (170 males and 129 females; age range: 19-90 years) treated at Bali Mandara Hospital from January to December 2022. Data on GDP levels and HbA1c values were collected and classified based on glycemic control. The correlation between GDP and HbA1c levels was tested using Spearman’s test. Results: The mean HbA1c value was not significantly different between the sexes and age groups, with higher values found in the 45-59 years age group and in women (7.88 ± 0.20%). The GDP ranged from 72-594 mg/dL, with a mean value of 181.45 ± 4.43 mg/dL. A significant positive correlation was observed between GDP and the HbA1c level (p<0.05). Poor glycemic control was found in 54.18% of the patients based on HbA1c and 69.23% based on GDP. Conclusions: Correlation between HbA1c levels and GDP is crucial for determining accurate and effective diabetes management strategies in clinical practice.

Author Biographies

Putu Dyah Sartika Sari, Faculty of Information Technology and Science, Universitas Hindu Indonesia

Department of Biology, Faculty of Information Technology and Science, Universitas Hindu Indonesia

Ni Ketut Ayu Juliasih, Faculty of Information Technology and Science, Universitas Hindu Indonesia

Department of Biology, Faculty of Information Technology and Science, Universitas Hindu Indonesia

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